Trial intelligence / Profile preview

REVELUTION-2: Leuprolide + Abiraterone vs Relugolix + Abiraterone for Advanced Prostate Cancer

NCT06650579Phase 3Recruiting

Sponsor
Emory University
Start
Jan 2025
Primary completion
Jul 2029
Modality
Peptides, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in prostate cancer (PCa) comparing Leuprolide + AA + Prednisone + RT with Relugolix + AA + Prednisone + RT (2 arms). Primary endpoints: Incidence of ambulatory systolic blood pressure > 140 or diastolic > 90 up to 12 months, Need for new or escalated anti-hypertensive medication up to 12 months and 1 more. Started Jan 2025; status: recruiting.

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Drugs

tissue-plasminogen activatorleuprolide
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Conditions

prostate cancer (PCa)

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