Trial intelligence / Profile preview

Triple Combination Therapy in Advanced HFpEF

NCT06655480Phase 2Recruiting

Start
Mar 2025
Primary completion
Dec 2027
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of empagliflozin, sacubitril + valsartan and finerenone in heart failure with preserved ejection fraction (HFpEF) (2 arms). Primary endpoints: Change in myocardial extracellular volume at 52 weeks, 6-Minute Walk Distance at 52 weeks and 3 more. Started Mar 2025; status: recruiting.

02

Drugs

empagliflozinsacubitril + valsartanfinerenone
03

Conditions

heart failure with preserved ejection fraction (HFpEF)

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