Trial intelligence / Profile preview

RESTOR: Rapamycin and Everolimus Study Towards Older Rejuvenation

NCT06658093Phase 1Recruiting

Sponsor
UT Health San Antonio
Start
Mar 2026
Primary completion
Jul 2028
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of sirolimus and everolimus in aging (7 arms), sponsored by UT Health San Antonio. Primary endpoints: Pharmacokinetics of mTOR inhibitor in blood at 12 months, PD measure of inhibition of mTOR activity in blood cells - p-rpS6 at 12 months and 1 more. Started Mar 2026; status: recruiting.

02

Drugs

sirolimuseverolimus
03

Conditions

aging

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