Trial intelligence / Profile preview

CD19 CAR T Cells for Refractory Autoimmune Diseases

NCT06688799Phase 2Recruiting

Sponsor
Beijing Gaobo Hospital
Start
Nov 2024
Primary completion
Mar 2026
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of CD19 CAR-T cells in systemic lupus erythematosus (SLE), Sjogren's syndrome, systemic sclerosis (SSc) and 3 more, sponsored by Beijing Gaobo Hospital. Primary endpoints: Dose-limiting toxicity at 28 days, Adverse events at 30 days and 1 more. Started Nov 2024; status: recruiting.

02

Drugs

CD19 CAR-T cells
03

Conditions

systemic lupus erythematosus (SLE)Sjogren's syndromesystemic sclerosis (SSc)antiphospholipid syndrome (APS)idiopathic inflammatory myopathy (IIM)

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