Trial intelligence / Profile preview

GF-CART01 in Relapsed or Refractory B-Cell Hematological Malignancies

NCT06703892Phase 1Recruiting

Sponsor
GenomeFrontier Therapeutics, Inc.
Start
Jun 2025
Primary completion
Mar 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of GF-CART01 in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), primary mediastinal large B-cell lymphoma (PMBCL) and 1 more, sponsored by GenomeFrontier Therapeutics, Inc. Primary endpoints: Maximum Tolerated Dose at 28 days and Safety and tolerability of GF-CART01 at 1 year. Started Jun 2025; status: recruiting.

02

Drugs

GF-CART01
03

Conditions

diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)primary mediastinal large B-cell lymphoma (PMBCL)high grade B-cell lymphoma (HGBCL)

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