Trial intelligence / Profile preview

CB IL-10/IL-15 CD19-CAR NK in B-cell NHL

NCT06707259Phase 1Recruiting

Sponsor
Second Affiliated Hospital of Zhejiang University School of Medicine
Start
Dec 2024
Primary completion
Dec 2026
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-cd19 interleukin-10 + interleukin-15 chimeric antigen receptor natural killer cells in B-cell non-Hodgkin lymphoma, sponsored by Second Affiliated Hospital of Zhejiang University School of Medicine. Primary endpoint: Incidence of dose limiting toxicity at 28 days. Started Dec 2024; status: recruiting.

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Drugs

anti-cd19 interleukin-10 + interleukin-15 chimeric antigen receptor natural killer cells
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Conditions

B-cell non-Hodgkin lymphoma

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