Trial intelligence / Profile preview

Safety and PK/PD of LPH-5 in Healthy Participants

NCT06722820Phase 1Not yet recruiting

Sponsor
Lophora
Start
Apr 2025
Primary completion
Nov 2025
Modality
Orthosteric Ligands
01

Overview

Phase 1, randomised, double-blind trial of LPH-5 in major depressive disorder (MDD) and treatment-resistant depression (TRD) (6 cohorts), sponsored by Lophora. Primary endpoints: Incidence and severity of adverse events (AEs), Incidence of laboratory abnormalities and 1 more. Planned start Apr 2025; status: not yet recruiting.

02

Drugs

LPH-5
03

Conditions

major depressive disorder (MDD)treatment-resistant depression (TRD)

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