Trial intelligence / Profile preview

Fourth-Generation CAR-T in Hematologic Malignancies

NCT06758713Phase 1Recruiting

Sponsor
The Third Affiliated Hospital of Southern Medical University
Start
Jan 2025
Primary completion
Dec 2028
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of Fourth-Generation CAR-T in multiple myeloma (MM), B cell lymphoma and hematologic malignancy (4 arms), sponsored by The Third Affiliated Hospital of Southern Medical University. Primary endpoints: Number of patients with dose-limiting toxicity at 30 days, Maximum Tolerated Dose at 30 days and 3 more. Started Jan 2025; status: recruiting.

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Drugs

Fourth-Generation CAR-T
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Conditions

multiple myeloma (MM)B cell lymphomahematologic malignancy

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