Trial intelligence / Profile preview

Mitoxantrone Liposome + Bu/Cy Conditioning for High-Risk AML

NCT06758726Not yet recruiting

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
Dec 2024
Primary completion
Oct 2026
Modality
Lipid-based Nanoparticles, CAR-T Cells, Small Molecules
01

Overview

Open-label, single-arm trial of mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells in acute myeloid leukemia (AML), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoint: 1 year-relapsed free survival. Planned start Dec 2024; status: not yet recruiting.

02

Drugs

mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells
03

Conditions

acute myeloid leukemia (AML)

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