Trial intelligence / Profile preview

CART123 in Relapsed/Refractory CD123+ Hematologic Malignancies

NCT06765876Phase 1Active, not recruiting

Sponsor
Institute of Hematology and Blood Transfusion
Start
Oct 2024
Primary completion
Dec 2028
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of CART123 in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), acute lymphoblastic leukemia (ALL) and 1 more, sponsored by Institute of Hematology and Blood Transfusion. Primary endpoints: Safety and tolerability of autologous CART123 cells at 24 months, Rate of hematological recovery at 24 months and 1 more. Started Oct 2024; status: active, not recruiting.

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Drugs

CART123
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)acute lymphoblastic leukemia (ALL)Blastic plasmacytoid dendritic cell neoplasm (BPDCN)

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