Trial intelligence / Profile preview

PRISM: PRecIsion in SCLC Via a Multicohort Study

NCT06769126Phase 2Recruiting

Sponsor
SWOG Cancer Research Network
Start
Nov 2025
Primary completion
Dec 2028
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 2, randomised, open-label trial of saruparib, ceralasertib and monalizumab in small cell lung cancer (SCLC) (6 cohorts), sponsored by SWOG Cancer Research Network. Primary endpoints: Screen success rate up to 3 years and Progression-Free Survival up to 3 years. Started Nov 2025; status: recruiting.

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Drugs

saruparibceralasertibmonalizumab
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Conditions

small cell lung cancer (SCLC)

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