Trial intelligence / Profile preview

Rollover Platform Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT06788509Phase 1Enrolling by invitation

Sponsor
Janssen Pharmaceutical
Start
Dec 2024
Primary completion
Jan 2028
Modality
IgG Antibodies, Antibody Conjugates, Small Molecules
Countries
15
01

Overview

Phase 1, open-label, single-arm trial of rezetamig, JNJ-67856633, ibrutinib, JNJ-64264681, JNJ-74856665 and 4 more in acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), myelodysplastic syndrome (MDS) and 3 more, sponsored by Janssen Pharmaceutical. Primary endpoint: Number of Participants with Serious Adverse Events (SAEs) and Grade Greater than or equals to (>=) 3 Related Adverse Events (AEs). Started Dec 2024; status: enrolling by invitation.

02

Drugs

rezetamigJNJ-67856633ibrutinibJNJ-64264681JNJ-74856665
03

Conditions

acute myeloid leukemia (AML)non-Hodgkin lymphoma (NHL)myelodysplastic syndrome (MDS)chronic lymphocytic leukemia (CLL)solid tumor

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