Trial intelligence / Profile preview

REPRESS: PCSK9i in ACS

NCT06791031Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jan 2026
Primary completion
Dec 2027
Modality
Antisense DNA, Conjugated siRNA, MicroRNA (miRNA)
01

Overview

Randomised, open-label trial of evolocumab, alirocumab and inclisiran in acute coronary syndrome (ACS) (2 arms), sponsored by West China Hospital of Sichuan University. Primary endpoint: Absolute change in the minimum fibrous cap thickness of target lesions at 6 months. Planned start Jan 2026; status: not yet recruiting.

02

Drugs

evolocumabalirocumabinclisiran
03

Conditions

acute coronary syndrome (ACS)

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