Trial intelligence / Profile preview

68Ga-FAPI PET to Predict T-DXd Response in HER2+ Breast Cancer Brain Metastases

NCT06797622Phase 2Not yet recruiting

Sponsor
Fudan University
Start
Feb 2025
Primary completion
Jan 2027
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab deruxtecan in HER2-positive breast cancer and brain metastases, sponsored by Fudan University. Primary endpoint: Difference of baseline heterogeneity index at 6 weeks. Planned start Feb 2025; status: not yet recruiting.

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Drugs

trastuzumab deruxtecan
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Conditions

HER2-positive breast cancerbrain metastases

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