Trial intelligence / Profile preview

Etavopivat Drug-Drug Interaction Study with Midazolam, Digoxin, Rosuvastatin, Pitavastatin, and Metformin

NCT06813924Phase 1Completed

Sponsor
Novo Nordisk
Start
Feb 2025
Primary completion
May 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of etavopivat in sickle cell disease (SCD) and thalassemia (5 arms), sponsored by Novo Nordisk. Primary endpoints: Maximum observed plasma concentration at Day 3 and Area under the plasma concentration-time curve from 0 hours to infinity at Day 3. Started Feb 2025; status: completed.

02

Drugs

etavopivat
03

Conditions

sickle cell disease (SCD)thalassemia

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