Trial intelligence / Profile preview

MK-5684 pharmacokinetics in renal impairment

NCT06814132Phase 1Completed

Sponsor
Merck & Co.
Start
Apr 2025
Primary completion
Oct 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of opevesostat (3 arms), sponsored by Merck & Co. Primary endpoints: Area Under the Concentration Versus Time Curve from 0 to Infinity at 72 hours, Area Under the Concentration Versus Time Curve From 0 to the Time of the Last Quantifiable Sample at 72 hours and 6 more. Started Apr 2025; status: completed.

02

Drugs

opevesostat

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