Trial intelligence / Profile preview

INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

NCT06818812Phase 1Active, not recruiting

Sponsor
Incyte
Start
Mar 2025
Primary completion
Mar 2027
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of INCB186748 in solid tumor, pancreatic ductal adenocarcinoma (PDAC) and colorectal cancer (CRC) (6 arms), sponsored by Incyte. Primary endpoints: Dose Limiting Toxicities up to 28 days, Treatment-emergent Adverse Events and 1 more. Started Mar 2025; status: active, not recruiting.

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Drugs

INCB186748
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Conditions

solid tumorpancreatic ductal adenocarcinoma (PDAC)colorectal cancer (CRC)

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