Trial intelligence / Profile preview

UWD-CD19 in Refractory Autoimmune Diseases

NCT06821659Phase 2Not yet recruiting

Sponsor
Peking University Third Hospital
Start
Nov 2026
Primary completion
Dec 2027
Modality
CAR-T Cells
01

Overview

Phase 2, open-label, single-arm trial of anti-CD19 CAR-T cells in systemic lupus erythematosus (SLE), systemic sclerosis (SSc), inflammatory myopathy (IIM) and 2 more, sponsored by Peking University Third Hospital. Primary endpoints: Safety of UWD-CD19 cell injection and Maximum tolerated dose at 28 days. Planned start Nov 2026; status: not yet recruiting.

02

Drugs

anti-CD19 CAR-T cells
03

Conditions

systemic lupus erythematosus (SLE)systemic sclerosis (SSc)inflammatory myopathy (IIM)Antineutrophil cytoplasmic antibody-associated vasculitis (AAV)Sjögren's syndrome

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