Trial intelligence / Profile preview

SONIC: Sonrotoclax Ramp-Up in CLL, SLL, and MCL

NCT06839053Phase 2Recruiting

Sponsor
Fred Hutchinson Cancer Center
Start
Jun 2025
Primary completion
Aug 2028
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 2, open-label trial of sonrotoclax in chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and mantle cell lymphoma (MCL) (2 arms), sponsored by Fred Hutchinson Cancer Center. Primary endpoints: Incidence of adverse events at Day 12, Percentage of patients who reach an 80mg dose of sonrotoclax at Day 4 and 1 more. Started Jun 2025; status: recruiting.

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Drugs

sonrotoclax
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Conditions

chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)mantle cell lymphoma (MCL)

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