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TALENT: Talazoparib With or Without Enzalutamide in mCRPC With HRR Mutations

NCT06844383Phase 2Recruiting

Sponsor
Prostate Cancer Clinical Trials Consortium
Start
May 2026
Primary completion
Mar 2029
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of talazoparib in metastatic castration-resistant prostate cancer (mCRPC) (2 arms), sponsored by Prostate Cancer Clinical Trials Consortium. Primary endpoint: Radiographic Progression-Free Survival at 42 months. Started May 2026; status: recruiting.

02

Drugs

talazoparib
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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