Trial intelligence / Profile preview

Metformin and Alendronate Gel with PRF in Chronic Periodontitis

NCT06856369Phase 4Active, not recruiting

Sponsor
Bahria University
Start
Jan 2025
Primary completion
Feb 2026
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of metformin 1% gel and alendronate in chronic periodontitis (3 arms), sponsored by Bahria University. Primary endpoints: Reduction in intra-bony defect depth at 12 months, Reduction in vertical bone loss at 12 months and 2 more. Started Jan 2025; status: active, not recruiting.

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Drugs

metformin 1% gelalendronate
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Conditions

chronic periodontitis

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