Trial intelligence / Profile preview

HYPERION CCA: Systemic Therapy +/- Liver-directed RT for Advanced Intrahepatic Cholangiocarcinoma

NCT06858735Phase 2Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Jun 2025
Primary completion
Nov 2028
Countries
1
01

Overview

Phase 2, randomised, open-label trial in intrahepatic cholangiocarcinoma (ICC) comparing Experimental Arm - Liver-RT + Durvalumab with Standard of Care Arm - Durvalumab + Gemcitabine + Cisplatin (2 arms). Primary endpoints: Overall Survival and Safety and Adverse Events. Started Jun 2025; status: recruiting.

02

Drugs

durvalumab
03

Conditions

intrahepatic cholangiocarcinoma (ICC)

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