Trial intelligence / Profile preview

LCAR-AIO in relapsed/refractory autoimmune diseases

NCT06866080Phase 1Withdrawn

Sponsor
Legend Biotech Corporation
Start
Jun 2025
Primary completion
Jun 2025
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of LCAR-AIO in systemic lupus erythematosus (SLE), Antineutrophil cytoplasmic antibody-associated vasculitis (AAV), systemic sclerosis (SSc) and 1 more, sponsored by Legend Biotech Corporation. Primary endpoints: Systemic Lupus Erythematosus Disease Activity Index 2000 at 104 weeks, Birmingham Vasculitis Activity Score at 104 weeks and 4 more. Planned start Jun 2025; status: withdrawn.

02

Drugs

LCAR-AIO
03

Conditions

systemic lupus erythematosus (SLE)Antineutrophil cytoplasmic antibody-associated vasculitis (AAV)systemic sclerosis (SSc)idiopathic inflammatory myopathy (IIM)

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