Trial intelligence / Profile preview

PF-08046032 Monotherapy and Combination Therapy in Advanced Malignancies

NCT06870487Phase 1Terminated

Sponsor
Pfizer
Start
May 2025
Primary completion
Apr 2026
Modality
Antibody-Drug Conjugates (ADCs)
Countries
2
01

Overview

Phase 1, open-label trial of PF-08046032 in peripheral T-cell lymphoma (PTCL), diffuse large B-cell lymphoma (DLBCL), classical Hodgkin lymphoma (cHL) and 3 more (3 arms), sponsored by Pfizer. Primary endpoints: Dose Limiting Toxicities up to 28 days, Adverse Events up to 90 days and 2 more. Started May 2025; status: terminated.

02

Drugs

PF-08046032
03

Conditions

peripheral T-cell lymphoma (PTCL)diffuse large B-cell lymphoma (DLBCL)classical Hodgkin lymphoma (cHL)head and neck squamous cell carcinoma (HNSCC)melanoma

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