Trial intelligence / Profile preview

Image-guided Photodynamic Therapy (PDT) Treatment of Pre-malignant and Malignant Oral Lesions

NCT06876038Phase 2Not yet recruiting

Sponsor
University of Massachusetts Boston
Start
Sep 2026
Primary completion
May 2028
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of 5-aminolevulinic acid in oral cancer, oral leukoplakia, oral lichen planus (OLP) and 1 more, sponsored by University of Massachusetts Boston. Primary endpoint: Efficacy of 5-ALA based PDT to treat HGD-OPML. Planned start Sep 2026; status: not yet recruiting.

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Drugs

5-aminolevulinic acid
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Conditions

oral canceroral leukoplakiaoral lichen planus (OLP)oral squamous cell carcinoma (OSCC)

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