Trial intelligence / Profile preview

CLL1 and CD38 Dual-Target CAR-T in r/r AML

NCT06880354Phase 1Recruiting

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
May 2025
Primary completion
Mar 2028
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of CLL1 and CD38 dual-target CAR-T cell injection in acute myeloid leukemia (AML), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoints: Dose-Limiting Toxicity Rate at 28 days and Adverse Events at 96 weeks. Started May 2025; status: recruiting.

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Drugs

CLL1 and CD38 dual-target CAR-T cell injection
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Conditions

acute myeloid leukemia (AML)

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