Trial intelligence / Profile preview

Efficacy and Safety of QL2108 vs Dupixent in Moderate-to-Severe Atopic Dermatitis

NCT06884891Phase 3

Key facts

Status
Not yet recruiting
Start
Apr 2025
Primary completion
May 2027
Modality
Monoclonal Antibodies
Drugs
QL2108
Conditions
atopic dermatitis (AD)
01

Overview

Phase 3, randomised, double-blind trial of QL2108 in atopic dermatitis (AD), sponsored by Qilu Pharmaceutical. Primary endpoint: Proportion of patients achieving EASI-75 at 16 weeks. Planned start Apr 2025; status: not yet recruiting.

02

Design

Study design
RandomizedDouble-blind
03

Who it enrols

Adults with moderate-to-severe atopic dermatitis with a disease history of >= 1 year and inadequate response to topical treatments (implied by moderate-severe criteria).

04

Endpoints

Primary

  • Proportion of patients achieving EASI-75

Secondary

  • Proportion of patients achieving EASI-75

  • Proportion of patients achieving IGA-TS

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