Trial intelligence / Profile preview

GLM101 in PMM2-CDG (POLAR Trial)

NCT06892288Phase 3Active, not recruiting

Sponsor
Glycomine
Start
Jul 2025
Primary completion
Aug 2026
Countries
10
01

Overview

Phase 3, randomised, double-blind trial in phosphomannomutase 2 deficiency (PMM2-CDG) comparing GLM101 with Placebo -> GLM101 (2 arms). Primary endpoint: International Cooperative Ataxia Rating Scale at 24 weeks. Started Jul 2025; status: active, not recruiting.

02

Drugs

GLM101
03

Conditions

phosphomannomutase 2 deficiency (PMM2-CDG)

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