Trial intelligence / Profile preview

BNT324 and BNT327 in Advanced Lung Cancer

NCT06892548Phase 2Recruiting

Sponsor
BioNTech SE
Start
May 2025
Primary completion
Sep 2028
Modality
Monoclonal Antibodies, Bispecific Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
10
01

Overview

Phase 2, randomised, open-label trial of db-1311 and pumitamig in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) (8 arms), sponsored by BioNTech SE. Primary endpoints: Dose Limiting Toxicities at 21 days, Treatment-Emergent Adverse Events at 90 days and 2 more. Started May 2025; status: recruiting.

02

Drugs

db-1311pumitamig
03

Conditions

non-small cell lung cancer (NSCLC)small cell lung cancer (SCLC)

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