Trial intelligence / Profile preview

Safety and Efficacy of PSMA-UCAR T in Refractory CRPC

NCT06895811Phase 1Active, not recruiting

Sponsor
Shanghai Changzheng Hospital
Start
Mar 2025
Primary completion
Jul 2026
Modality
Gene Editing, Prophylactic Vaccines, Gene Silencing
Countries
1
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Overview

Phase 1, open-label, single-arm trial of Universal BCMA-CD19 CAR-T in prostate cancer (PCa), sponsored by Shanghai Changzheng Hospital. Primary endpoints: Adverse Events assessed by CTCAE v5.0 at 6 months, Cytokine Release Syndrome grading at 6 months and 1 more. Started Mar 2025; status: active, not recruiting.

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Drugs

Universal BCMA-CD19 CAR-T
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Conditions

prostate cancer (PCa)

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