Trial intelligence / Profile preview

Inhaled vs Oral Afatinib Dimaleate in Healthy Smokers

NCT06897735Phase 1Terminated

Start
Nov 2025
Primary completion
May 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial of afatinib in lung cancer, oral cancer and melanoma (2 arms). Primary endpoints: Maximum observed plasma concentration at 48 hours and Afatinib dimaleate urinary concentrations at 96 hours. Started Nov 2025; status: terminated.

02

Drugs

afatinib
03

Conditions

lung canceroral cancermelanoma

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