Trial intelligence / Profile preview

Absolute Bioavailability of Vepdegestrant in Healthy Participants

NCT06911788Phase 1Completed

Sponsor
Pfizer
Start
Apr 2025
Primary completion
May 2025
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of vepdegestrant in hormone receptor-positive/HER2-negative breast cancer, sponsored by Pfizer. Primary endpoint: Dose-normalized Area Under the Curve From Time Zero to Extrapolated Infinite Time. Started Apr 2025; status: completed.

02

Drugs

vepdegestrant
03

Conditions

hormone receptor-positive/HER2-negative breast cancer

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