Trial intelligence / Profile preview

Zanzalintinib With Pembrolizumab and Cetuximab in R/M HNSCC

NCT06912087Phase 1Recruiting

Sponsor
University of Chicago
Start
Sep 2025
Primary completion
Jun 2027
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 1, open-label trial of zanzalintinib in squamous cell carcinoma of the head and neck (HNSCC) (4 arms), sponsored by University of Chicago. Primary endpoints: Maximally Tolerated Dose at 28 days and Recommended Phase II Dose. Started Sep 2025; status: recruiting.

02

Drugs

zanzalintinib
03

Conditions

squamous cell carcinoma of the head and neck (HNSCC)

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