Trial intelligence / Profile preview

Carfilzomib and Belatacept for Antibody-Mediated Rejection in Kidney Transplant

NCT06918990Phase 1Recruiting

Sponsor
National Institute of Allergy and Infectious Diseases
Start
May 2026
Primary completion
Jun 2027
Modality
Reversible Covalent Inhibitors, Irreversible Covalent Inhibitors, Fc-Fusion Proteins
Countries
1
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Overview

Phase 1, open-label, single-arm trial of carfilzomib and belatacept in kidney transplant rejection, sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoint: Proportion of subjects who do not meet a stopping rule for safety at 12 months. Started May 2026; status: recruiting.

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Drugs

carfilzomibbelatacept
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Conditions

kidney transplant rejection

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