Trial intelligence / Profile preview

NEODISCO: Neoadjuvant Gemcitabine/Cisplatin + Pembrolizumab vs Upfront Surgery in Cholangiocarcinoma

NCT06923475Phase 3Recruiting

Sponsor
Amsterdam University Medical Center
Start
Apr 2026
Primary completion
Nov 2028
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab, gemcitabine and Cisplatin micelle injection (HA132) in extrahepatic cholangiocarcinoma (eCCA) (2 arms), sponsored by Amsterdam University Medical Center. Primary endpoint: Event Free Survival at 18 months. Started Apr 2026; status: recruiting.

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Drugs

pembrolizumabgemcitabineCisplatin micelle injection (HA132)
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Conditions

extrahepatic cholangiocarcinoma (eCCA)

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