Trial intelligence / Profile preview

ABBV-637 or ABBV-155 + ERAS-801 in EGFR-Amplified Glioblastoma

NCT06934889Phase 1Recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Apr 2025
Primary completion
Apr 2028
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
1
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Overview

Phase 1, randomised, open-label trial of ABBV-637 and mirzotamab clezutoclax in glioblastoma (GBM) and Gliosarcoma (GS) (4 cohorts), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Dose Limiting Toxicity at 1 year. Started Apr 2025; status: recruiting.

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Drugs

ABBV-637mirzotamab clezutoclax
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Conditions

glioblastoma (GBM)Gliosarcoma (GS)

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