Trial intelligence / Profile preview

225Ac-SSO110 in ES-SCLC and MCC

NCT06939036Phase 2Terminated

Sponsor
Ariceum Therapeutics
Start
Jul 2025
Primary completion
Dec 2025
Modality
Peptide-Drug Conjugates
Countries
2
01

Overview

Phase 2, open-label, single-arm trial of 225Ac-SSO110 in small cell lung cancer (SCLC) and Merkel cell carcinoma (MCC), sponsored by Ariceum Therapeutics. Primary endpoints: Safety, tolerability, and Recommended Phase 2 Dose (RP2D) of 225Ac-SSO110 in combination with SoC at 42 days, Preliminary anti-tumor activity of 225Ac-SSO110 in combination with SoC at RP2D at 42 days and 1 more. Started Jul 2025; status: terminated.

02

Drugs

225Ac-SSO110
03

Conditions

small cell lung cancer (SCLC)Merkel cell carcinoma (MCC)

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