Trial intelligence / Profile preview

PK DDI Study of AZD2389 with Midazolam, Caffeine, and Bupropion

NCT06973005Phase 1Completed

Sponsor
AstraZeneca
Start
May 2025
Primary completion
Jul 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of AZD2389 in metabolic dysfunction-associated steatohepatitis (MASH), sponsored by AstraZeneca. Primary endpoints: Ratio of treatment to reference based on Cmax, Ratio of treatment to reference based on AUCinf and 2 more. Started May 2025; status: completed.

02

Drugs

AZD2389
03

Conditions

metabolic dysfunction-associated steatohepatitis (MASH)

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