Trial intelligence / Profile preview

CART-EGFR-IL13Rα2 Cells in Newly Diagnosed Glioblastoma

NCT06973096Phase 1Active, not recruiting

Sponsor
University of Pennsylvania
Start
Jul 2025
Primary completion
Jul 2042
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label trial of bivalent CAR-T (anti-EGFR) in glioblastoma (GBM) (2 cohorts), sponsored by University of Pennsylvania. Primary endpoints: Treatment-related adverse events at 15 years and Treatment-limiting toxicities at 28 days. Started Jul 2025; status: active, not recruiting.

02

Drugs

bivalent CAR-T (anti-EGFR)
03

Conditions

glioblastoma (GBM)

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