Trial intelligence / Profile preview

Tacabrutideg vs Pirtobrutinib in Relapsed/Refractory CLL or SLL

NCT06973187Phase 3Recruiting

Sponsor
BeOne Medicines
Start
Sep 2025
Primary completion
Apr 2028
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
24
01

Overview

Phase 3, randomised, open-label trial of tacabrutideg in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) (2 arms), sponsored by BeOne Medicines. Primary endpoint: Progression-Free Survival per Independent Review Committee. Started Sep 2025; status: recruiting.

02

Drugs

tacabrutideg
03

Conditions

chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)

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