Trial intelligence / Profile preview

PF-08046037 alone or with sasanlimab in advanced malignancies

NCT06974734Phase 1Terminated

Sponsor
Pfizer
Start
May 2025
Primary completion
Mar 2026
Modality
Immunomodulatory ADCs, Small Molecules, Monoclonal Antibodies
Countries
2
01

Overview

Phase 1, open-label trial of PF-08046037 in non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), melanoma and 1 more (6 arms), sponsored by Pfizer. Primary endpoints: Adverse Events, Laboratory Abnormalities and 2 more. Started May 2025; status: terminated.

02

Drugs

PF-08046037
03

Conditions

non-small cell lung cancer (NSCLC)head and neck squamous cell carcinoma (HNSCC)melanomapancreatic ductal adenocarcinoma (PDAC)

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