Trial intelligence / Profile preview

124I-AT-01 PET/CT Imaging in CAPS and Anakinra-Induced Amyloidosis

NCT06974877Phase 1Recruiting

Sponsor
National Institute of Allergy and Infectious Diseases
Start
Sep 2025
Primary completion
Jul 2031
Modality
Peptides
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of 124I-evuzamitide in amyloidosis, sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoints: Change in organ-specific 124I AT-01 uptake from baseline at 24 months and Frequency of CAPS disease flares after exposure to 124I AT 01 at 2 years. Started Sep 2025; status: recruiting.

02

Drugs

124I-evuzamitide
03

Conditions

amyloidosis

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