Trial intelligence / Profile preview

Bispecific Antibody Therapy in Lupus Nephritis

NCT06975787Phase 1Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Dec 2025
Primary completion
Sep 2029
Modality
Antibody Conjugates, Bispecific Antibodies, Monoclonal Antibodies
Countries
6
01

Overview

Phase 1 trial of vonsetamig and odronextamab in lupus nephritis (LN), sponsored by Regeneron Pharmaceuticals. Primary endpoints: Dose Limiting Toxicities up to 56 days and Treatment Emergent Adverse Events. Started Dec 2025; status: recruiting.

02

Drugs

vonsetamigodronextamab
03

Conditions

lupus nephritis (LN)

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