Trial intelligence / Profile preview

Rilzabrutinib in Sickle-cell Disease

NCT06975865Phase 3Recruiting

Sponsor
Sanofi
Start
Aug 2025
Primary completion
Jul 2027
Modality
Small Molecules
Countries
14
01

Overview

Phase 3, randomised, double-blind trial in sickle cell disease (SCD) comparing Rilzabrutinib with Placebo (2 arms). Primary endpoint: Annualized rate of clinical vaso-occlusive crises (VOC) at 52 weeks. Started Aug 2025; status: recruiting.

02

Drugs

rilzabrutinib
03

Conditions

sickle cell disease (SCD)

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