Trial intelligence / Profile preview

Loncastuximab and Roflumilast Added to R-CHOP for Treatment Naïve High-Risk DLBCL

NCT06977711Phase 1Recruiting

Sponsor
UT Health San Antonio
Start
Jun 2025
Primary completion
Oct 2026
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of loncastuximab tesirine and roflumilast in diffuse large B-cell lymphoma (DLBCL), sponsored by UT Health San Antonio. Primary endpoint: Adverse Events up to 24 weeks. Started Jun 2025; status: recruiting.

02

Drugs

loncastuximab tesirineroflumilast
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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