Trial intelligence / Profile preview

CAR19-BCMA CAR-T Cell Therapy for Relapsed/Refractory Plasma Cell Neoplasms and Lymphomas/Leukemias

NCT06986434Phase 1Not yet recruiting

Sponsor
Academy of Military Medical Sciences
Start
Apr 2026
Primary completion
May 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of CAR19-BCMA CAR-T cells (Affiliated Hospital to Academy of Military Medical Sciences) in plasma cell neoplasm, lymphoma, leukemia and 2 more, sponsored by Academy of Military Medical Sciences. Primary endpoints: Incidence of treatment-related adverse events at 3 years and Maximal Tolerable Dose at 28 days. Planned start Apr 2026; status: not yet recruiting.

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Drugs

CAR19-BCMA CAR-T cells (Affiliated Hospital to Academy of Military Medical Sciences)
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Conditions

plasma cell neoplasmlymphomaleukemiamultiple myeloma (MM)systemic light chain amyloidosis

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