Trial intelligence / Profile preview

Ponsegromab in Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

NCT06989437Phase 3Recruiting

Sponsor
Pfizer
Start
Oct 2025
Primary completion
Jan 2028
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Countries
21
01

Overview

Phase 3, randomised, double-blind trial of ponsegromab in cachexia (3 arms), sponsored by Pfizer. Primary endpoints: Percent change from baseline in body weight at 12 weeks and Functional Assessment of Anorexia/Cachexia Therapy 5-item Anorexia Symptom Scale scores at 12 weeks. Started Oct 2025; status: recruiting.

02

Drugs

ponsegromab
03

Conditions

cachexia

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