Trial intelligence / Profile preview

Psilocybin and MDMA for Post-traumatic Stress Disorder (PTSD)

NCT06989957Phase 1Recruiting

Sponsor
Johns Hopkins University
Start
Sep 2025
Primary completion
Aug 2028
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 1, randomised, double-blind trial of psilocybin and midomafetamine in post-traumatic stress disorder (PTSD) (2 arms), sponsored by Johns Hopkins University. Primary endpoints: Incidence of Adverse Events at 30 weeks, Columbia Suicide Severity Rating Scale at 33 weeks and 3 more. Started Sep 2025; status: recruiting.

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Drugs

psilocybinmidomafetamine
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Conditions

post-traumatic stress disorder (PTSD)

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