Trial intelligence / Profile preview

SGB-3383 in Healthy Volunteers

NCT06995326Phase 1Not yet recruiting

Sponsor
SanegeneBio
Start
Jun 2025
Primary completion
Aug 2026
Modality
Conjugated siRNA, Chemically Modified siRNA
01

Overview

Phase 1, randomised, double-blind trial in IgA nephropathy (IgAN), Complement 3 glomerulopathy (C3G), atypical hemolytic uremic syndrome (aHUS) and 2 more comparing SGB-3383 with Placebo (2 arms). Primary endpoint: Number of Participants with Adverse Events. Planned start Jun 2025; status: not yet recruiting.

02

Drugs

SGB-3383
03

Conditions

IgA nephropathy (IgAN)Complement 3 glomerulopathy (C3G)atypical hemolytic uremic syndrome (aHUS)paroxysmal nocturnal hemoglobinuria (PNH)immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN)

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