Trial intelligence / Profile preview

Anti-Mesothelin CAR-T in Advanced Solid Tumors

NCT07010523Phase 1Recruiting

Sponsor
Zhejiang University
Start
Oct 2024
Primary completion
Oct 2026
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-mesothelin CAR vector-transduced autologous T lymphocytes in mesothelioma, pancreatic cancer (PC), biliary tract cancer (BTC) and 8 more, sponsored by Zhejiang University. Primary endpoints: Adverse Events (AEs) at 2 years, Serious Adverse Events (SAEs) at 2 years and 3 more. Started Oct 2024; status: recruiting.

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Drugs

anti-mesothelin CAR vector-transduced autologous T lymphocytes
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Conditions

mesotheliomapancreatic cancer (PC)biliary tract cancer (BTC)lung cancerovarian cancer

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